| Chemical Properties | Back Directory | [Melting point ]
71-73 °C | [Boiling point ]
313.3±15.0 °C(Predicted) | [density ]
1.06±0.1 g/cm3(Predicted) | [solubility ]
sol ethanol, acetic acid. | [pka]
-0.63±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
2-Ethoxypyridine 1-Oxide is used for acyl activating agent for peptide synthesis;[1] catalyst for phosphotriester bond formation.[2] | [Preparation]
2-Ethoxypyridine 1-Oxide is prepared from 2-ethoxypyridine and Hydrogen Peroxide[3] or 2-chloropyridine 1-oxide and
ethanolic Sodium Ethoxide.[4] | [References]
1. Paquette, L. A. JACS 1965, 87, 5186.
2. Efimov, V. A.; Chakhmakhcheva, O. G.; Ovchinnikov, Y. A. Nucleic Acids Res. 1985, 13, 3651.
3. Newbold, G. T.; Spring, F. S. JCS 1948, 1864.
4. Gardner, J. N.; Katritzky, A. R. JCS 1957, 4375. |
|
|