| Identification | Back Directory | [Name]
calcium bis[2-butyl-3-(1,2-diphenylhydrazino)-3-oxopropionate] | [CAS]
34461-73-9 | [Synonyms]
Eumotol
B-64114
Rheumotol
Bumadizon calcium
Bumadizone calcium
Bumadizone calcium salt
calcium bis[2-butyl-3-(1,2-diphenylhydrazino)-3-oxopropionate]
Bis[2-(N,N'-diphenylhydrazinocarbonyl)hexanoic acid]calcium salt | [EINECS(EC#)]
252-048-9 | [Molecular Formula]
C38H42CaN4O6 | [MOL File]
34461-73-9.mol | [Molecular Weight]
690.841 |
| Hazard Information | Back Directory | [Uses]
Bumadizone calcium is the calcium salt of Bumadizone (HY-17481). Bumadizone calcium is a non-steroidal anti-inflammatory drug, that exhibits potential in ameliorating chronic inflammatory diseases. Bumadizone calcium is irritant to the gastric lining, which leads to gastric bleeding and ulceration[1]. | [Definition]
ChEBI: An organic calcium salt having 2-[(1,2-diphenylhydrazino)carbonyl]hexanoate as the counterion. Used (as its hemihydrate) for treatment of rheumatoid arthritis. | [References]
[1] Nour SA, et al., Bumadizone calcium dihydrate microspheres compressed tablets for colon targeting: formulation, optimization and in vivo evaluation in rabbits. Drug Deliv. 2015 May;22(3):286-97. DOI:10.3109/10717544.2014.889779 |
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