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34503-87-2

34503-87-2 Structure

34503-87-2 Structure
IdentificationBack Directory
[Name]

6-Methylheptanoyl-L-A2bu-L-Thr-L-A2bu-cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-)
[CAS]

34503-87-2
[Synonyms]

Polymyxin B2
Unii-99sjo09vh2
polymyxin B2Q: What is polymyxin B2 Q: What is the CAS Number of polymyxin B2
6-Methylheptanoyl-L-A2bu-L-Thr-L-A2bu-cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-)
L-Threonine, N2-(6-methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-, cyclic (10-4)-peptide
N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methylheptanamide
[Molecular Formula]

C55H96N16O13
[MOL File]

34503-87-2.mol
[Molecular Weight]

1189.47
Chemical PropertiesBack Directory
[alpha ]

225461 -112.4° (2% Acetic acid)
[solubility ]

Methanol (Slightly), Water (Slightly)
[form ]

Solid
[color ]

White to Pale Brown
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

Polymyxin B2 is a cyclic lipopeptide antibiotic. It is a component of Polymyxin B which is used as a last-line treatment for multi-drug resistant gram-negative bacteria.
[Definition]

ChEBI: Polymyxin B2 is a polymyxin having a 6-methylheptanoyl group at the amino terminus.
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