3458-22-8

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3458-22-8 Structure

Identification	Back Directory
[Name] IPD
[CAS] 3458-22-8
[Synonyms] Yoshi864 Yoshi-864 NSC102627 Yoshi 864 Improsulfan HCl IPD Hydrochloride Improsulfan hydrochloride Bis(3-mesyloxypropyl)amine hydrochloride
[Molecular Formula] C8H19NO6S2.ClH
[MDL Number] MFCD01696892
[MOL File] 3458-22-8.mol
[Molecular Weight] 325.832

Chemical Properties	Back Directory
[Melting point ] 94-95°

Safety Data	Back Directory
[Hazardous Substances Data] 3458-22-8(Hazardous Substances Data)
[Toxicity] LD50 i.v. in rats: 75 mg/kg (Brock, Kuhlmann)

Hazard Information	Back Directory
[Uses] Yoshi-864 (NSC-102627) is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor[1].
[References] [1] Gale GR, et al. Comparative effects of Yoshi-864 and busulfan on certain transplantable murine tumors. Proc Soc Exp Biol Med. 1975 May;149(1):98-101. DOI:10.3181/00379727-149-38751

3458-22-8 suppliers list

Company Name:	Suzhou Rovathin Foreign Trade Co.,Ltd
Tel:	0512-65816829 18662214788
Website:	http://www.rovathin.com/

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