| Identification | Back Directory | [Name]
HPCG | [CAS]
3458-69-3 | [Synonyms]
HPCG
N-[(3-Hydroxy-2-pyridinyl)carbonyl]glycine
2-[(3-hydroxypyridin-2-yl)formamido]acetic acid | [Molecular Formula]
C8H8N2O4 | [MDL Number]
MFCD00941661 | [MOL File]
3458-69-3.mol | [Molecular Weight]
196.16 |
| Hazard Information | Back Directory | [Description]
HPCG is a HIF-1α prolyl hydroxylase inhibitor. | [Uses]
2-(3-Hydroxypicolinamido)acetic acid is a 2OG oxygenase inhibitor with an IC50 value of 3.4 μM. 2-(3-Hydroxypicolinamido)acetic acid can be used as a functional probe for potential therapeutic research[1]. | [References]
[1] Woon EC, et al. Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase. J Med Chem. 2012 Mar 8;55(5):2173-84. DOI:10.1021/jm201417e |
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Key Organics Ltd.
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+44 (0) 1840-212137 |
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www.keyorganics.net |
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