ChemicalBook--->CAS DataBase List--->34595-33-0

34595-33-0

34595-33-0 Structure

34595-33-0 Structure
IdentificationBack Directory
[Name]

5-AMino-2-(piperidin-1-yl)benzonitrile
[CAS]

34595-33-0
[Synonyms]

5-AMino-2-(piperidin-1-yl)benzonitrile
Benzonitrile, 5-amino-2-(1-piperidinyl)-
[Molecular Formula]

C12H15N3
[MDL Number]

MFCD14617260
[MOL File]

34595-33-0.mol
[Molecular Weight]

201.27
Chemical PropertiesBack Directory
[Boiling point ]

431.5±35.0 °C(Predicted)
[density ]

1.16±0.1 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[pka]

5.97±0.10(Predicted)
Hazard InformationBack Directory
[Synthesis]

5-NITRO-2-PIPERIDINOBENZENECARBONITRILE

32188-75-3

5-AMino-2-(piperidin-1-yl)benzonitrile

34595-33-0

General procedure for the synthesis of 5-amino-2-(piperidin-1-yl)benzonitrile from 5-nitro-2-piperidinobenzonitrile: 5-nitro-2-(piperidin-1-yl)benzonitrile was dissolved in an appropriate amount of solvent, and the reduction reaction was carried out by the addition of NaBH4 for 30 min. Upon completion of the reaction, 2.0 g of yellow solid (compound 11) was added for subsequent processing.

[References]

[1] Patent: CN106892871, 2017, A. Location in patent: Paragraph 0135; 0138; 0139
[2] Patent: US2006/79696, 2006, A1. Location in patent: Page/Page column 38
[3] Patent: EP1176140, 2002, A1. Location in patent: Page 54
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