| Identification | Back Directory | [Name]
3-hydroxylidocaine | [CAS]
34604-55-2 | [Synonyms]
3-hydroxylidocaine
m-Hydroxylidocaine
-hydroxy Lidocaine
Lidocaine Impurity 24
2-(Diethylamino)-3'-hydroxy-2',6'-dimethylacetanilide
2-(Diethylamino)-N-(3-hydroxy-2,6-dimethylphenyl)acetamide
Acetamide, 2-(diethylamino)-N-(3-hydroxy-2,6-dimethylphenyl)- | [Molecular Formula]
C14H22N2O2 | [MDL Number]
MFCD00869530 | [MOL File]
34604-55-2.mol | [Molecular Weight]
250.34 |
| Chemical Properties | Back Directory | [Melting point ]
192-195°C | [Boiling point ]
390.8±42.0 °C(Predicted) | [density ]
1.103±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
10.18±0.23(Predicted) | [color ]
Light Brown |
| Hazard Information | Back Directory | [Description]
3’-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. | [Chemical Properties]
Light Brown Solid | [Uses]
A metabolite of Lidocaine (L397800). | [Definition]
ChEBI: 3-Hydroxylidocaine is an amino acid amide. | [References]
[1] J S WANG. Involvement of CYP1A2 and CYP3A4 in lidocaine N-deethylation and 3-hydroxylation in humans.[J]. Drug Metabolism and Disposition, 2000, 28 8: 959-965.
[2] J?RGEN HERMANSSON. Metabolism of Lidocaine in Human Liver in Vitro[J]. Basic & Clinical Pharmacology & Toxicology, 1980, 47 1: 49-52. DOI: 10.1111/j.1600-0773.1980.tb02024.x |
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