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3464-68-4

3464-68-4 Structure

3464-68-4 Structure
IdentificationBack Directory
[Name]

1-Demethylcolchicine
[CAS]

3464-68-4
[Synonyms]

1-Demethylcolchicine
Colchicine Impurity 19
1-O-Demethyl Colchicine
Colchicine 1-Demethyl Impurity
Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1-hydroxy-2,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-
[Molecular Formula]

C21H23NO6
[MOL File]

3464-68-4.mol
[Molecular Weight]

385.41
Hazard InformationBack Directory
[Uses]

1-Demethylcolchicine is a derivative of Colchicine (C640000) an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
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