| Identification | Back Directory | [Name]
Ac-Ile-Glu-Thr-Asp-AMC | [CAS]
348079-17-4 | [Synonyms]
N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine
N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine | [Molecular Formula]
C31H41N5O12 | [MDL Number]
MFCD01630896 | [MOL File]
348079-17-4.mol | [Molecular Weight]
675.69 |
| Hazard Information | Back Directory | [Uses]
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity[1]. | [References]
[1] V Frost, et al. Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells. Oncogene. 2001 May 17;20(22):2737-48. DOI:10.1038/sj.onc.1204367 |
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