| Identification | Back Directory | [Name]
Amisulbrom | [CAS]
348635-87-0 | [Synonyms]
Amisulbrom
Amisulbrom 1
Amisulbrom Standard
Amisulbrom solution
Amisulbrom@100 μg/mL in Methanol
Amisulbrom@1000 μg/mL in Acetonitrile
AmisμLbrom, 100 μg /μL in Acetonitrile
Amisulbrom Solution in Methanol, 100μg/mL
3-(3-Bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide
3-[(3-Bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl]-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide
1H-1,2,4-Triazole-1-sulfonamide, 3-[(3-bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl]-N,N-dimethyl- | [Molecular Formula]
C13H13BrFN5O4S2 | [MDL Number]
MFCD11865361 | [MOL File]
348635-87-0.mol | [Molecular Weight]
466.31 |
| Chemical Properties | Back Directory | [Melting point ]
128～132℃ | [Boiling point ]
651.5±65.0 °C(Predicted) | [density ]
1.85±0.1 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
DMSO (Sparingly), Methanol (Slightly, Sonicated) | [form ]
neat | [pka]
-5.12±0.50(Predicted) | [BRN ]
11328670 | [Henry's Law Constant]
4.7×101 mol/(m3Pa) at 25℃, MacBean (2012) | [Major Application]
agriculture
environmental | [InChI]
1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 | [InChIKey]
BREATYVWRHIPIY-UHFFFAOYSA-N | [SMILES]
CN(C)S(=O)(=O)n1cnc(n1)S(=O)(=O)n2c(C)c(Br)c3ccc(F)cc23 | [LogP]
1.980 (est) | [EPA Substance Registry System]
1H-1,2,4-Triazole-1-sulfonamide, 3-[(3-bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl]-N,N-dimethyl- (348635-87-0) |
| Hazard Information | Back Directory | [Description]
A sulfonamide fungicide that is used to control a range of common infections. It has a low aqueous solubility, is slightly volatile with a calculated moderate mobility. There is not a high risk of the substance leaching to groundwater. It may be persistent in soil systems but is not expected to persist in water systems. It has a low mammalian toxicity but it is considered to be a reproduction toxicant. It is moderately toxic to birds and honeybees but poses a greater risk to aquatic species and earthworms. | [Uses]
Amisulbrom is a fungicide used in pesticide formulations in the treatment of blight in vegetation. | [Definition]
ChEBI: A member of the class of bromoindoles that is 3-bromo-6-fluoro-2-methylindole substituted at position 1 by a 1-(dimethylsulfamyl)-1,2,4-triazole-3-sulfonyl group. A fungicide for use on potatoes to control late blight (Phytophthora infestans)
nd downy mildew [Plasmopara viticola). It has a low mammalian toxicity but it is considered to be a reproduction toxicant, is moderately toxic to birds and honey bees but poses a greater risk to aquatic species and earthworms. | [General Description]
Amisulbrom is classified under the triazole group of fungicides. It contains a sulfone functional group with potent bioactivity. | [Mechanism of action]
Qil (Quinone Inside Inhibitor) action. Respiration inhibitor. | [Synthesis]
The commercial production of amisulbrom follows a concise three-step sulfonamide coupling process. First, 3-bromo-6-fluoro-2-methylindole is N-sulfonylated with 1H-1,2,4-triazole-1-sulfonyl chloride. The resulting indolyl sulfonyl triazole is then reacted with chlorosulfonyl isocyanate in dichloromethane, followed by in situ dimethylamine addition to form the sulfonamide linkage. Crude amisulbrom is purified by crystallisation from ethyl acetate/hexane. | [Pesticide Type]
Fungicide |
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Sigma-Aldrich
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