| Identification | Back Directory | [Name]
Corynecin II | [CAS]
35098-52-3 | [Synonyms]
Corynecin Ⅱ
Corynecin II
(βR)-β-Hydroxy-4-nitro-L-phenylalanine
(2S,3R)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propanoic acid
(2S,3R)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propionic acid
Propanamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]- | [Molecular Formula]
C12H16N2O5 | [MDL Number]
MFCD01695923 | [MOL File]
35098-52-3.mol | [Molecular Weight]
268.27 |
| Hazard Information | Back Directory | [Description]
Corynecin II is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It inhibits the growth of Gram-positive and Gram-negative bacteria, including S. faecalis, S. aureus, B. subtilis, E. coli, P. aeruginosa, P. vulgaris, S. sonnei, S. typhosa, and K. pneumoniae (MICs = 5.2-83 μg/ml). | [Uses]
Corynecin II is a chloramphenicol-like acyl nitrophenylpropylamine. | [Uses]
Corynecin II is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin II is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin II shows a similar species selectivity. |
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