ChemicalBook--->CAS DataBase List--->350992-13-1

350992-13-1

350992-13-1 Structure

350992-13-1 Structure
IdentificationBack Directory
[Name]

BIFEPRUNOX MESYLATE
[CAS]

350992-13-1
[Synonyms]

Du-127090
BIFEPRUNOX MESYLATE
(7-[4-([1,1-Biphenyl]-3-ylmethyl)-1-piperazinyl])
7-[4-([1,1'-Biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone Mesylate
7-[4-([1,1'-Biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate
[Molecular Formula]

C24H23N3O2.CH4O3S
[MDL Number]

MFCD09840052
[MOL File]

350992-13-1.mol
[Molecular Weight]

481.57
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

257-259°C
[storage temp. ]

-20?C Freezer
[solubility ]

DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[InChIKey]

ONWKHSGOYGLGPO-UHFFFAOYSA-N
[SMILES]

O=C1OC2=C(N3CCN(CC4=CC=CC(C5=CC=CC=C5)=C4)CC3)C=CC=C2N1.CS(=O)(O)=O
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

Used as an antipsychotic compound. Activates the serotonin 5-hydroxytryptamine (5-HT)1A receptor
[Biological Activity]

Bifeprunox (DU-127,090) is an atypical antipsychotic. Bifeprunox is a dopamine D2 receptor (D2R) partial agonist th at exhibits 5-HT1A agonist properties.
[in vivo]

Bifeprunox (0.001-2.5 mg/kg) reduces marble burying in mice[2].
Bifeprunox (4-250 μg/kg) influences nicotine-seeking behaviour in response to drug-associated stimuli in rats[3].

[storage]

Store at -20°C
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315
[Precautionary statements ]

P302+P352
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Skin Irrit. 2
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