| Identification | Back Directory | [Name]
BIFEPRUNOX MESYLATE | [CAS]
350992-13-1 | [Synonyms]
Du-127090
BIFEPRUNOX MESYLATE
(7-[4-([1,1-Biphenyl]-3-ylmethyl)-1-piperazinyl])
7-[4-([1,1'-Biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone Mesylate
7-[4-([1,1'-Biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate | [Molecular Formula]
C24H23N3O2.CH4O3S | [MDL Number]
MFCD09840052 | [MOL File]
350992-13-1.mol | [Molecular Weight]
481.57 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
257-259°C | [storage temp. ]
-20?C Freezer | [solubility ]
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [InChIKey]
ONWKHSGOYGLGPO-UHFFFAOYSA-N | [SMILES]
O=C1OC2=C(N3CCN(CC4=CC=CC(C5=CC=CC=C5)=C4)CC3)C=CC=C2N1.CS(=O)(O)=O |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
Used as an antipsychotic compound. Activates the serotonin 5-hydroxytryptamine (5-HT)1A receptor | [Biological Activity]
Bifeprunox (DU-127,090) is an atypical antipsychotic. Bifeprunox is a dopamine D2 receptor (D2R) partial agonist th at exhibits 5-HT1A agonist properties. | [in vivo]
Bifeprunox (0.001-2.5 mg/kg) reduces marble burying in mice[2].
Bifeprunox (4-250 μg/kg) influences nicotine-seeking behaviour in response to drug-associated stimuli in rats[3]. | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315 | [Precautionary statements ]
P302+P352 | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Skin Irrit. 2 |
|
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Cckinase, Inc.
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