| Identification | Back Directory | [Name]
BPP 9A | [CAS]
35115-60-7 | [Synonyms]
DK84D
BPP 9A
SQ 20881
teprotide
PYR-WPRPQIPP
BPP 9A USP/EP/BP
Teprotide, SQ20881
BPP 9a
Teprotide, SQ20881
Bradykinin potentiator BPP9a
BRADYKININ POTENTIATING FACTOR
BRADYKININ POTENTIATOR PEPTIDE 9A
Bradykinin-potentiating peptide-9a
PYR-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO
BRADYKININ POTENTIATOR FACTOR BPP9A
GLP-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO
PGLU-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO
PYR-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO-OH
Bradykinin-potentiating peptide BPP-9a
PYROGLU-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO
ANGIOTENSIN-CONVERTING ENZYME INHIBITOR
H-pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro-OH
Angiotensin Converting Enzyme Inhibitor(ACEI)
BPP 9a Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro-OH
Angiotensin Converting Enzyme Inhibitor, BPP 9a
GLP-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO: GLP-WPRPQIPP
Angiotensin converting enzyme inhibitor, ≥95% (TLC)
pGlu-L-Trp-L-Pro-L-Arg-L-Pro-L-Gln-L-Ile-L-Pro-L-Pro-OH
5-Oxo-L-Pro-L-Trp-L-Pro-L-Arg-L-Pro-L-Gln-L-Ile-L-Pro-L-Pro-OH
L-Proline, 5-oxo-L-prolyl-L-tryptophyl-L-prolyl-L-arginyl-L-prolyl-L-glutaminyl-L-isoleucyl-L-prolyl- | [Molecular Formula]
C53H76N14O12 | [MDL Number]
MFCD00076208 | [MOL File]
35115-60-7.mol | [Molecular Weight]
1101.26 |
| Chemical Properties | Back Directory | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
water: soluble 1 mg/mL, clear, colorless | [form ]
Powder | [pka]
3.44±0.20(Predicted) | [biological source]
synthetic (organic) | [Water Solubility ]
water: soluble 1mg/mL, clear, colorless | [Sequence]
{Glp}-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro | [InChIKey]
UUUHXMGGBIUAPW-CSCXCSGISA-N |
| Hazard Information | Back Directory | [Uses]
Teprotide is an inhibitor of angiotensin-converting enzyme (ACE) inhibitor. Teprotide can be used to study hypertensive[1]. | [Definition]
ChEBI: Teprotide is a peptide. | [Enzyme inhibitor]
This snake venom nonapeptide (FW = 1101.26 g/mol), also known as
teprotide, V-6-1, and SQ-20881, from the venom of Bothrops jararaca
potentiates the action of bradykinin, while inhibiting angiotensin I-
converting enzyme (IC50 = 0.01 μM for the human testicular enzyme). The
corresponding octapeptide lacking one C-terminal proline residues also
inhibits. | [References]
[1] J C McKenzie, et al. Reduction in hypertension-induced protein synthesis in the rat pulmonary trunk after treatment with teprotide (SQ 20881). Proc Soc Exp Biol Med. 1984, 177, 2. DOI:10.3181/00379727-177-41959 |
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