| Identification | Back Directory | [Name]
SB-423562 | [CAS]
351490-27-2 | [Synonyms]
SB-423562
Namodenoson
SB-423562(free base)
Inhibitor,CaSR,Calcium-sensing receptor,inhibit,SB 423562,SB423562,SB-423562
Benzenepropanoic acid, 4-cyano-3-[(2R)-3-[[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino]-2-hydroxypropoxy]-
(R)-3-(4-cyano-3-(3-((1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)phenyl)propanoic acid | [Molecular Formula]
C26H32N2O4 | [MDL Number]
MFCD19443794 | [MOL File]
351490-27-2.mol | [Molecular Weight]
436.54 |
| Chemical Properties | Back Directory | [Boiling point ]
676.4±55.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO: 5 mg/mL (11.45 mM) | [form ]
Solid | [pka]
4.49±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research. | [storage]
Store at -20°C | [References]
[1] Kumar S, et al. An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation. Bone. 2010 Feb;46(2):534-42. DOI:10.1016/j.bone.2009.09.028 |
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