ChemicalBook--->CAS DataBase List--->35263-73-1

35263-73-1

35263-73-1 Structure

35263-73-1 Structure
IdentificationBack Directory
[Name]

LHRH
[CAS]

35263-73-1
[Synonyms]

LHRH
LH-RH(OH)
gly(10)-lhr
PYR-HWSYGLRPG
LHRH, Gly(10)-
LHRH USP/EP/BP
[GLY-OH10]-LH-RH
[PYR]HWSYGLRPG-OH
LH-RH (FREE ACID)
GONADOTROPIN-RELEASING HORMONE
LUTEINIZING HORMONE-RELEASING HORMONE
GLP-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY
PYR-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY
PGLU-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY
GnRH (free acid), Gonadorelin (free acid)
PYR-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY-OH
PYROGLU-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY
(gly-oh10)-luteinizing hormone*releasing hormone
LUTEINIZING HORMONE-RELEASING HORMONE (FREE ACID)
LUTEINIZING HORMONE-RELEASING HORMONE (LH-RH), HUMAN
[Gly-OH10]-LH-RH, LH-RH, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly
((S)-5-Oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolylglycine
[Molecular Formula]

C55H74N16O14
[MDL Number]

MFCD00167539
[MOL File]

35263-73-1.mol
[Molecular Weight]

1183.27
Chemical PropertiesBack Directory
[density ]

1.54±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

Solid
[pka]

3.67±0.10(Predicted)
[color ]

White to off-white
[Sequence]

{Pyr}-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H360
[Precautionary statements ]

P201-P308+P313
[Hazard Codes ]

T
[Risk Statements ]

60
[Safety Statements ]

53-22-36/37/39-45
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

LHRH (free acid), the luteinizing hormone-releasing hormone, is a neuropeptide hypothalamic. LHRH regulates reproduction. LHRH can be used for the research of cancer[1].
[References]

[1] Schally AV, et, al. Discovery of LHRH and development of LHRH analogs for prostate cancer treatment. Prostate. 2017 Jun;77(9):1036-1054. DOI:10.1002/pros.23360
[2] Pearce TR, et, al. Peptide targeted lipid nanoparticles for anticancer drug delivery. Adv Mater. 2012 Jul 24;24(28):3803-22, 3710. DOI:10.1002/adma.201200832
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