| Identification | Back Directory | [Name]
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)- | [CAS]
3542-63-0 | [Synonyms]
CDK9-IN-10
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)- | [Molecular Formula]
C22H16O5 | [MDL Number]
MFCD34469988 | [MOL File]
3542-63-0.mol | [Molecular Weight]
360.36 |
| Chemical Properties | Back Directory | [Melting point ]
220-221 °C(Solv: ethyl acetate (141-78-6); benzene (71-43-2)) | [Boiling point ]
621.1±55.0 °C(Predicted) | [density ]
1.381±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, away from moisture and light | [solubility ]
DMSO : ≥ 100 mg/mL (277.50 mM) | [form ]
Solid | [pka]
7.06±0.40(Predicted) | [color ]
Yellow to brown |
| Hazard Information | Back Directory | [Uses]
CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811)[1]. | [IC 50]
CDK9 | [References]
[1] Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381. DOI:10.1016/j.bioorg.2018.08.028 |
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| Company Name: |
cjbscvictory
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| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
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