| Identification | Back Directory | [Name]
N4-(7-chloro-4-quinolyl)-N1,N1-diethylpentane-1,4-diamine dihydrochloride | [CAS]
3545-67-3 | [Synonyms]
Chloroquine HCl
Unii-nt0J0815S5
Einecs 222-592-1
Aralen hydrochloride
Chloroquine dihydrochloride
4-((4-Amino-1-methylbutyl)amino)-7-chloroquinoline dihydrochloride
Quinoline, 4-((4-amino-1-methylbutyl)amino)-7-chloro-, dihydrochloride
N4-(7-chloro-4-quinolyl)-N1,N1-diethylpentane-1,4-diamine dihydrochloride
4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine,dihydrochloride
1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, dihydrochloride (9ci) | [EINECS(EC#)]
222-592-1 | [Molecular Formula]
C18H28Cl3N3 | [MDL Number]
MFCD06804666 | [MOL File]
3545-67-3.mol | [Molecular Weight]
392.794 |
| Hazard Information | Back Directory | [Uses]
Anti-amebic. | [in vivo]
Chloroquine dihydrochloride (80 mg/kg, i.p.) does not prevent the growth of the triple-negative MDA-MB-231 cells with high or low TLR9 expression levels in the orthotopic mouse model[2].
TLR7 and TLR9 inhibition using IRS-954 or Chloroquine dihydrochloride significantly inhibits tumour growth in the mouse xenograft model. HCC development in the DEN/NMOR rat model is also significantly inhibited by Chloroquine[3]. | [IC 50]
Plasmodium; Malaria; TLRs; SARS-COV-2; HIV-1 |
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