| Identification | Back Directory | [Name]
3-[4-(1,3-benzodioxol-5-yl)-2-oxo-3-butenyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one | [CAS]
355428-84-1 | [Synonyms]
3HOIBA01
3HOI BA 01
3HOI-BA-01
3-HOI-BA-01
3-[4-(1,3-benzodioxol-5-yl)-2-oxo-3-butenyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one | [Molecular Formula]
C19H15NO5 | [MOL File]
355428-84-1.mol | [Molecular Weight]
337.326 |
| Chemical Properties | Back Directory | [Boiling point ]
633.350±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.419±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
11.447±0.20(predicted) |
| Hazard Information | Back Directory | [Uses]
3HOI-BA-01 is amTORinhibitor.3HOI-BA-01reduces infarct size and inducedautophagyin a murine myocardial ischemia/reperfusion injury model[1]. | [References]
[1] Huang L, et al. The AMPK Agonist PT1 and mTOR Inhibitor 3HOI-BA-01 Protect Cardiomyocytes After Ischemia Through Induction of Autophagy. J Cardiovasc Pharmacol Ther. 2016;21(1):70-81. DOI:10.1177/1074248415581177 |
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