| Identification | Back Directory | [Name]
rubrofusarin | [CAS]
3567-00-8 | [Synonyms]
NSC 258316
rubrofusarin
5,6-Dihydroxy-8-methoxy-2-methyl-4H-naphtho[2,3-b]pyran-4-one
4H-Naphtho[2,3-b]pyran-4-one, 5,6-dihydroxy-8-methoxy-2-methyl- | [Molecular Formula]
C15H12O5 | [MDL Number]
MFCD30146414 | [MOL File]
3567-00-8.mol | [Molecular Weight]
272.25 |
| Chemical Properties | Back Directory | [Melting point ]
214℃ (benzene ) | [Boiling point ]
438.7±45.0 °C(Predicted) | [density ]
1.432±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
3.83±0.40(Predicted) | [color ]
yellow to orange | [InChI]
1S/C15H12O5/c1-7-3-10(16)14-12(20-7)5-8-4-9(19-2)6-11(17)13(8)15(14)18/h3-6,17-18H,1-2H3 | [InChIKey]
FPNKCZKRICBAKG-UHFFFAOYSA-N | [SMILES]
[o]1c2c([c](cc1C)=O)c(c3c(c2)cc(cc3O)OC)O |
| Hazard Information | Back Directory | [Uses]
Rubrofusarin is useful for treating chronic restraint stress-induced depressive symptoms. | [Definition]
ChEBI: A member of the class of benzochromenones that is benzo[g]chromen-4-one carrying two additional hydroxy substituents at positions 5 and 6 as well as methyl and methoxy substituents at positions 2 and 8 respectively. An orange polyketide pigmen
that is a common intermediate in many different fungal biosynthetic pathways. | [Biochem/physiol Actions]
Rubrofusarin is an orange polyketide pigment produced by Fusarium graminearum and other fungal species that exhibit potent anti-cancer and anti-mycobacterial activities. Rubrofusarin is a mycotoxin that inhibits human DNA topoisomerase II-α.. Additionally, Rubrofusarin shows a significant anti-estrogenic activity. | [storage]
+4°C |
|
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