| Identification | Back Directory | [Name]
8-Aminoadenosine triphosphate | [CAS]
35874-49-8 | [Synonyms]
8-NH2-ATP
8-Amino-ATP
8-Aminoadenosine triphosphate
8-Aminoadenosine 5'-triphosphate
Adenosine 5'-(tetrahydrogen triphosphate), 8-amino-
8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution | [Molecular Formula]
C10H17N6O13P3 | [MDL Number]
MFCD18643161 | [MOL File]
35874-49-8.mol | [Molecular Weight]
522.2 |
| Hazard Information | Back Directory | [Uses]
8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase[1][2]. | [References]
[1] Nancy L Krett, et al. 8-amino-adenosine is a potential therapeutic agent for multiple myeloma. Mol Cancer Ther. 2004 Nov;3(11):1411-20. PMID:15542780
[2] Yuji Matsuzaki, et al. ATP-association to intrabacterial nanotransportation system in Vibrio cholera. Med Mol Morphol. 2015 Dec;48(4):225-34. DOI:10.1007/s00795-015-0105-4 |
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