| Identification | Back Directory | [Name]
CYCLOPENTANE-1,2-DICARBOXYLIC ACID ANHYDRIDE | [CAS]
35878-28-5 | [Synonyms]
cis-cyclopentane-1,2-dicarboxylic anhydride
(1S,5R)-3-Oxabicyclo[3.3.0]octane-2,4-dione
CYCLOPENTANE-1,2-DICARBOXYLIC ACID ANHYDRIDE
cis-Tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)
(1R,2S)-Cyclopentane-1,2-dicarboxylic anhydride
cis-Cyclopentane-1,2-dicarboxylic acid anhydride
cis-tetrahydro-1H-cyclopenta[c]furan-1,3(4H)-dione
cis-tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione
(3aα,6aα)-Hexahydro-1H-cyclopenta[c]furan-1,3-dione
4,5,6,6a-tetrahydro-3aH-cyclopenta[c]furan-1,3-dione
cis-1,2-Cyclopentanedicarboxylic anhydride >=97.0% (GC)
3aα,5,6,6aα-Tetrahydro-1H-cyclopenta[c]furan-1,3(4H)-dione
1H-Cyclopenta[c]furan-1,3(3aH)-dione,tetrahydro-, (3aR,6aS)-rel- | [EINECS(EC#)]
252-773-0 | [Molecular Formula]
C7H8O3 | [MDL Number]
MFCD08060139 | [MOL File]
35878-28-5.mol | [Molecular Weight]
140.14 |
| Chemical Properties | Back Directory | [Melting point ]
73-74 °C | [Boiling point ]
84-86°C/0.5mm | [density ]
1.309±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [Appearance]
White to off-white Solid | [BRN ]
12396898 | [InChI]
InChI=1/C7H8O3/c8-6-4-2-1-3-5(4)7(9)10-6/h4-5H,1-3H2/t4-,5+ | [InChIKey]
NMSRALOLNIBERV-SYDPRGILNA-N | [SMILES]
O1C(=O)[C@]2([H])CCC[C@]2([H])C1=O |&1:3,8,r| |
| Hazard Information | Back Directory | [Uses]
cis-1,2-Cyclopentanedicarboxylic Anhydride functions as a reagent in the enantioselective synthesis of disubstituted proline derivatives and its application in synthesis of hepatitis C virus protease inhibitor telaprevir, Nrf2-Keap1 complex inhibitors preparation, binding mode and structural-activity relationship. | [Synthesis]
In a 250 ml aubergine flask, 2 g of cis-cyclopentyl-1,2dicarboxylic acid and 126.4 ml of acetic anhydride were added, heated and refluxed for 10 h. Excess acetic anhydride was removed under reduced pressure to obtain the crude cyclopentane-1,2-dicarboxyli |
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