| Identification | Back Directory | [Name]
PROSTAGLANDIN B1 | [CAS]
35900-16-4 | [Synonyms]
PGE1 ethyl ester
Alprostadil ethyl ester
Alprostadil EP Impurity I
Prostaglandin EP Impurity I
LVDCZROIKIHUKJ-QZCLESEGSA-N
PROSTAGLANDIN E1 ETHYL ESTER
Alprostadil (Prostaglandin E1) EP Impurity I
11α,15S-dihydroxy-9-oxo-prost-13E-en-1-oic acid, ethyl ester | [EINECS(EC#)]
806-708-3 | [Molecular Formula]
C22H38O5 | [MDL Number]
MFCD00133788 | [MOL File]
35900-16-4.mol | [Molecular Weight]
382.537 |
| Chemical Properties | Back Directory | [Boiling point ]
498.6±45.0 °C(Predicted) | [density ]
1.077±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO:50.0(Max Conc. mg/mL);130.71(Max Conc. mM)
DMF:50.0(Max Conc. mg/mL);130.71(Max Conc. mM)
Ethanol:30.0(Max Conc. mg/mL);78.42(Max Conc. mM)
PBS (pH 7.2):0.25(Max Conc. mg/mL);0.65(Max Conc. mM) | [pka]
13.85±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
Prostaglandin E1 ethyl ester (Prostaglandin E1 Et ester) is the esterified form of Prostaglandin E1 (PGE1; HY-B0131). Prostaglandin E1 (Alprostadil) is a prostaglandin receptor ligand that induces vasodilation and inhibits platelet aggregation[1]. | [storage]
Store at -20°C | [References]
[1] Sheu MT, et al. Investigation of the percutaneous penetration of prostaglandin E1 and its ethyl ester. J Control Release. 1998 Nov 13;55(2-3):153-60. DOI:10.1016/s0168-3659(98)00045-5 |
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