Identification | Back Directory | [Name]
ORM-3819 | [CAS]
360794-85-0 | [Synonyms]
ORM-3819 ORM3819,ORM 3819 ORM-3819 >=98% (HPLC) Benzaldehyde, 4-hydroxy-3-methoxy-2-nitro-, 2-[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazone | [Molecular Formula]
C19H19N5O5 | [MDL Number]
MFCD30738205 | [MOL File]
360794-85-0.mol | [Molecular Weight]
397.38 |
Hazard Information | Back Directory | [Biological Activity]
ORM-3819 is a potent inotropic agent th at binds to cardiac troponin C (cTnC) and sensitizes heart to Ca2+. AlsoORM-3819 is a selective and potent inhibitor of PDE III. ORM-3819 exhibits positive inotropic effects through Ca2+-sensitization and selective inhibition of PDE III. ORM-3819 was effective in vivo dog model of myocardial stunning. |
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
Company Name: |
Merck KGaA
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Tel: |
21-20338288 |
Website: |
www.sigmaaldrich.cn |
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