| Identification | Back Directory | [Name]
3'-DEOXYGUANOSINE | [CAS]
3608-58-0 | [Synonyms]
3'-DG
-1H-purin-6(9H)
3'-DEOXYGUANOSINE
Guanosine, 3'-deoxy-
3'-Deoxy-D-guanosine
2-Amino-9-((2R,3R,5S)
3'-DEOXYGUANOSINE USP/EP/BP
-3-hydroxy-5-(hydroxymethyl)
3'-deoxyguanosine monohydrate
2-Amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6(1H)-one
2-Amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-1H-purine-6(9H)-one
2-amino-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
2-azanyl-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
2-amino-9-[(2R,3R,5S)-3-hydroxy-5-methylol-tetrahydrofuran-2-yl]-3H-purin-6-one
2-AMino-9-((2R,3R,5S)-3-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one | [Molecular Formula]
C10H13N5O4 | [MDL Number]
MFCD00079149 | [MOL File]
3608-58-0.mol | [Molecular Weight]
267.24 |
| Chemical Properties | Back Directory | [Melting point ]
<300℃ (water ) | [density ]
2.08±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly), Water (Slightly, Heated, Sonicated) | [form ]
Solid | [color ]
White to Off-White | [InChI]
InChI=1S/C10H13N5O4/c11-10-13-7-6(8(18)14-10)12-3-15(7)9-5(17)1-4(2-16)19-9/h3-5,9,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,9+/m0/s1 | [InChIKey]
OROIAVZITJBGSM-OBXARNEKSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](O)C1 |
| Hazard Information | Back Directory | [Description]
3''-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors, in order to study structure-activity relationships.1,2 This compound can also be used to selectively impair transcription.3 | [Chemical Properties]
solid | [Uses]
3’-Deoxyguanosine is a derivative of guanosine, a ligand which may be complexe with enzymes such as purine nucleoside phosphorylase and receptors. Potential anti-amoebic agent. | [Definition]
ChEBI: 3'-deoxyguanosine is a 3'-deoxyribonucleoside having guanine as the nucleobase. It has a role as an EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor. It is a 3'-deoxyribonucleoside and a member of guanosines. | [References]
[1] FERNANDA CANDURI. Structure of human PNP complexed with ligands.[J]. Acta crystallographica. Section D, Biological crystallography, 2005, 61 Pt 7: 856-862. DOI: 10.1107/s0907444905005421
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[3] ROBERT W KING Matthew W J Marianne Zecher. Inhibition of the replication of a hepatitis C virus-like RNA template by interferon and 3’-deoxycytidine.[J]. Antiviral Chemistry and Chemotherapy, 2002, 13 6: 363-370. DOI: 10.1177/095632020201300604 |
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