| Identification | Back Directory | [Name]
Acetamide, 2-bromo-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]- | [CAS]
362678-28-2 | [Synonyms]
Acetamide, 2-bromo-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]- | [Molecular Formula]
C20H38BrNO3 | [MOL File]
362678-28-2.mol | [Molecular Weight]
420.42 |
| Chemical Properties | Back Directory | [Melting point ]
79-81 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
580.5±50.0 °C(Predicted) | [density ]
1.145±0.06 g/cm3(Predicted) | [solubility ]
DMF: 2 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): insol | [form ]
A solid | [pka]
12.50±0.46(Predicted) |
| Hazard Information | Back Directory | [Description]
SOBRAC is an irreversible inhibitor of acid ceramidase (Ki = 29.7 nM) and a derivative of the acid ceramidase inhibitor SABRAC .1 | [Uses]
SOBRAC is an irreversible inhibitor of acid ceramidase (Ceramidase) with a Ki of 29.7 nM, and it's also a derivative of the acid ceramidase inhibitor SABRAC (HY-165070)[1]. | [References]
1. Ordó?ez, Y.F., Abad, J.L., Aseeri, M., et al. Activity-based imaging of acid ceramidase in living cells J. Am. Chem. Soc. 141(19),7736-7742(2019). |
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