| Identification | Back Directory | [Name]
1H-Indole-3-carboxaldehyde, 2-(3,7-dimethyl-2-quinolinyl)hydrazone | [CAS]
364361-68-2 | [Synonyms]
1H-Indole-3-carbaldehyde(3,7-dimethyl-2-quinolinyl)hydrazone
1H-Indole-3-carboxaldehyde, 2-(3,7-dimethyl-2-quinolinyl)hydrazone | [Molecular Formula]
C20H18N4 | [MOL File]
364361-68-2.mol | [Molecular Weight]
314.38 |
| Chemical Properties | Back Directory | [Boiling point ]
559.8±50.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [solubility ]
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
DMSO: Sparingly soluble: 1-10 mg/ml | [pka]
10.97±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Endosidine 5 (ES5) inhibits EPS (extracellular polymeric substance) secretion and cell wall expansion. Endosidine 5 alters secretion of ECM (extracellular matrix) material in Penium margaritaceum by affecting the Golgi apparatus. Endosidine 5 interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm[1][2]. | [References]
[1] LoRicco JG, et al. Endosidin 5 disruption of the Golgi apparatus and extracellular matrix secretion in the unicellular charophyte Penium margaritaceum. Ann Bot. 2023 Jul 10;131(6):967-983. DOI:10.1093/aob/mcad054
[2] Shin J, et al. Targeting Recycling Endosomes to Potentiate mRNA Lipid Nanoparticles. Nano Lett. 2024 May 1;24(17):5104-5109. DOI:10.1021/acs.nanolett.3c04415 |
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