ChemicalBook--->CAS DataBase List--->36438-97-8

36438-97-8

36438-97-8 Structure

36438-97-8 Structure
IdentificationBack Directory
[Name]

1-METHYL-1,2,3,4-TETRAHYDRO-QUINOXALINE DIHYDROCHLORIDE
[CAS]

36438-97-8
[Synonyms]

4-Methyl-2,3-dihydro-1H-quinoxaline
Quinoxaline, 1,2,3,4-tetrahydro-1-methyl-
1-METHYL-1,2,3,4-TETRAHYDRO-QUINOXALINE DIHYDROCHLORIDE
1-Methyl-1,2,3,4-tetrahydroquinoxaline dihydrochloride, 95+%
4-methyl-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine dihydrochloride
1-METHYL-1,2,3,4-TETRAHYDRO-QUINOXALINE DIHYDROCHLORIDE ISO 9001:2015 REACH
[Molecular Formula]

C9H14Cl2N2
[MDL Number]

MFCD08544478
[MOL File]

36438-97-8.mol
[Molecular Weight]

221.127
Chemical PropertiesBack Directory
[Melting point ]

40.5-42℃
[Boiling point ]

163-169 °C(Press: 21 Torr)
[density ]

1.033±0.06 g/cm3(Predicted)
[pka]

7.41±0.20(Predicted)
[CAS DataBase Reference]

36438-97-8
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H335-H319-H315
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Questions And AnswerBack Directory
[Application]

Methyl-1,2,3,4-tetrahydroquinoxaline dihydrochloride exhibits glutamate receptor antagonism, high affinity for AMPA receptors (non-NMDA receptors), and strong inhibitory effects on the neurotoxicity of phycocyanin, thus inhibiting auditory convulsions. It also possesses high solubility and can serve as an inhibitor of phycocyanin neurotoxicity in its active ingredient. Furthermore, 1-methyl-1,2,3,4-tetrahydroquinoxaline dihydrochloride compounds are important intermediates in organic synthesis, used to prepare various fine chemical products, such as dyes (WO1999051688A1) or poly(phenylquinoxaline) derivatives, the latter being a crucial structural unit in organic polymer light-emitting diodes (LEDs).
Hazard InformationBack Directory
[Synthesis]

Take a 100 ml single-necked bottle, add 1-methyl-quinoxaline-6-carboxylic acid methyl ester (3) 3.76 g (0.02 mol), and add methanol 50 ml, stirring to dissolve, and then add slowly into the sodium borohydride 3.02 g (0.08 mol). 90 ° C. Reaction was carrie
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