| Identification | Back Directory | [Name]
1-METHYL-1,2,3,4-TETRAHYDRO-QUINOXALINE DIHYDROCHLORIDE | [CAS]
36438-97-8 | [Synonyms]
4-Methyl-2,3-dihydro-1H-quinoxaline Quinoxaline, 1,2,3,4-tetrahydro-1-methyl- 1-METHYL-1,2,3,4-TETRAHYDRO-QUINOXALINE DIHYDROCHLORIDE 1-Methyl-1,2,3,4-tetrahydroquinoxaline dihydrochloride, 95+% 4-methyl-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine dihydrochloride 1-METHYL-1,2,3,4-TETRAHYDRO-QUINOXALINE DIHYDROCHLORIDE ISO 9001:2015 REACH | [Molecular Formula]
C9H14Cl2N2 | [MDL Number]
MFCD08544478 | [MOL File]
36438-97-8.mol | [Molecular Weight]
221.127 |
| Questions And Answer | Back Directory | [Application]
Methyl-1,2,3,4-tetrahydroquinoxaline dihydrochloride exhibits glutamate receptor antagonism, high affinity for AMPA receptors (non-NMDA receptors), and strong inhibitory effects on the neurotoxicity of phycocyanin, thus inhibiting auditory convulsions. It also possesses high solubility and can serve as an inhibitor of phycocyanin neurotoxicity in its active ingredient. Furthermore, 1-methyl-1,2,3,4-tetrahydroquinoxaline dihydrochloride compounds are important intermediates in organic synthesis, used to prepare various fine chemical products, such as dyes (WO1999051688A1) or poly(phenylquinoxaline) derivatives, the latter being a crucial structural unit in organic polymer light-emitting diodes (LEDs). |
| Hazard Information | Back Directory | [Synthesis]
Take a 100 ml single-necked bottle, add 1-methyl-quinoxaline-6-carboxylic acid methyl ester (3) 3.76 g (0.02 mol), and add methanol 50 ml, stirring to dissolve, and then add slowly into the sodium borohydride 3.02 g (0.08 mol). 90 ° C. Reaction was carrie |
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