| Identification | Back Directory | [Name]
3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE | [CAS]
36499-49-7 | [Synonyms]
MB3
NC Blue 3
-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE
3-[2-Methyl-4-(diethylamino)phenyl]-3-(1,2-dimethyl-3-indolyl)phthalide
(2R,3S)-rel-4-Methylene-5-oxo-2-propyltetrahydrofuran-3-carboxylic acid
3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE
2-(2'-Methyl-4'-diethylaminophenyl)-3-(1',2'-dimethylindol-3'-yl)phthalide
3-(1,2-Dimethyl-3-indolyl)-3-[4-(diethylamino)-2-methylphenyl]phthalide>
3-[4-(Diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indol-3-yl)phthalide
3-[4-(diethylamino)-2-methylphenyl]-3-(1,2-dimethylindol-3-yl)-2-benzofuran-1-one
3-(4-(diethylaMino)-2-Methylphenyl)-3-(1,2-diMethyl-1H-indol-3-yl)isobenzofuran-1(3H)-one
3-[4-(Diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indole-3-yl)-1(3H)-isobenzofuranone
3-[4-(Diethylamino)-2-methylphenyl]-3- (1,2-dimethyl-1H-indol-3-yl)-1(3H)-Isobenzofuranone
1(3H)-Isobenzofuranone, 3-[4-(diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indol-3-yl)-
3-[2-Methyl-4-(diethylamino)phenyl]-3-(1,2-dimethyl-3-indolyl)phthalide
2-(2'-Methyl-4'-diethylaminophenyl)-3-(1',2'-dimethylindol-3'-yl)phthalide | [Molecular Formula]
C29H30N2O2 | [MDL Number]
MFCD08276348 | [MOL File]
36499-49-7.mol | [Molecular Weight]
438.56 |
| Chemical Properties | Back Directory | [Melting point ]
217 °C | [Boiling point ]
627.3±55.0 °C(Predicted) | [density ]
1.14 | [storage temp. ]
-20°C | [solubility ]
H2O: ≥10 mg/mL || DMSO: ≥20 mg/mL | [form ]
powder to crystal | [pka]
6.27±0.50(Predicted) | [color ]
White to Light yellow | [Water Solubility ]
H2O: ≥10mg/mL
DMSO: ≥20mg/mL | [InChI]
1S/C9H12O4/c1-3-4-6-7(8(10)11)5(2)9(12)13-6/h6-7H,2-4H2,1H3,(H,10,11)/t6-,7+/m1/s1 | [InChIKey]
SRQUTZJZABSZRQ-RQJHMYQMSA-N | [SMILES]
CCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O |
| Hazard Information | Back Directory | [Uses]
MB-3 has been used as a general control non-repressible 5 (GCN5) inhibitor:
- to study its effects on lamin A/C-associated pY19-Cav-2-mediated histone H3 acetylations
- to analyze its effects on the growth of Arabidopsis thaliana seedlings
- to study its effects on craniofacial chondrocyte maturation
| [Biological Activity]
MB-3 can modify the gene expression in murine embryonic stem cells as well as yeast. It hinders the acetyltransferase activity of general control non-repressible 5 (GCN5) by binding to acetyl CoA pocket present in GCN5.''MB-3 is a Gcn5 H at (Histone Acetyltransferase) inhibitor; anti-inflammatoryanti-carcinogenic. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
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