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365462-61-9

365462-61-9 Structure

365462-61-9 Structure
IdentificationBack Directory
[Name]

Benzamide, 5-chloro-N-(5-chloro-2-pyridinyl)-2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-hydroxy-
[CAS]

365462-61-9
[Synonyms]

AS1468240
AS-1468240
AS 1468240
Benzamide, 5-chloro-N-(5-chloro-2-pyridinyl)-2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-hydroxy-
[Molecular Formula]

C25H25Cl2N5O3
[MOL File]

365462-61-9.mol
[Molecular Weight]

514.4
Chemical PropertiesBack Directory
[Boiling point ]

592.2±50.0 °C(Predicted)
[density ]

1.414±0.06 g/cm3(Predicted)
[pka]

7.53±0.10(Predicted)
Hazard InformationBack Directory
[Description]

AS1468240 is a factor Xa inhibitor with significant oral anticoagulant activity.
[Uses]

AS1468240 is an orally active inhibitor for anticoagulant factor Xa (fXa), that inhibits human fXa with IC50 of 8.7 nM. AS1468240 prolongs the coagulation time in mice[1].
[References]

[1] Ishihara T, et al., Identification of potent orally active factor Xa inhibitors based on conjugation strategy and application of predictable fragment recommender system. Bioorg Med Chem. 2015 Jan 15;23(2):277-89. DOI:10.1016/j.bmc.2014.11.042
365462-61-9 suppliers list
Company Name: TargetMol Chemicals Inc.
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Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
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