| Identification | Back Directory | [Name]
Deoxyharringtonine | [CAS]
36804-95-2 | [Synonyms]
Deoxyharringtonine
Cephalotaxine, 3-[4-methyl (2R)-2-hydroxy-2-(3-methylbutyl)butanedioate]
(2R)-2-Hydroxy-2-(methoxycarbonyl)methyl-5-methylhexanoic acid (1S,3aR)-1,5,6,8,9,14bβ-hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-yl ester | [Molecular Formula]
C28H37NO8 | [MOL File]
36804-95-2.mol | [Molecular Weight]
515.6 |
| Hazard Information | Back Directory | [Uses]
Deoxyharringtonine is an alkaloid isolated from Cephalotaxus genus with significant anti-leukemic activity[1]. | [References]
[1] Joseph D Eckelbarger, et al. Synthesis of antiproliferative Cephalotaxus esters and their evaluation against several human hematopoietic and solid tumor cell lines: uncovering differential susceptibilities to multidrug resistance. Chemistry. 2008;14(14):4293-306. DOI:10.1002/chem.200701998 |
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