| Identification | Back Directory | [Name]
broxaldine | [CAS]
3684-46-6 | [Synonyms]
Aids112123
broxaldine
Aids-112123
Brobenzoxaldine
5,7-Bibromo-2-methylquinolin-8-ol
5,7-Dibromo-8-benzoyloxy-2-methylquinoline
5,7-Dibromo-2-methylquinoline-8-ol benzoate | [EINECS(EC#)]
222-971-1 | [Molecular Formula]
C17H11Br2NO2 | [MDL Number]
MFCD00865040 | [MOL File]
3684-46-6.mol | [Molecular Weight]
421.08 |
| Chemical Properties | Back Directory | [Boiling point ]
538.1±50.0 °C(Predicted) | [density ]
1.692±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 5 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: 1 mg/ml | [form ]
A solid | [pka]
0.73±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Broxaldine (Brobenzoxaldine) is an antiprotozoal agent. Broxaldine inhibits Clostridium difficile with a MIC value of 4 μM, and has antifungal effects[1][2]. | [References]
[1] Hazra SK, et al. Therapeutic trial of a combination of broxyquinoline and brobenzoxaldine in the treatment of leprosy. Lepr India. 1979 Oct;51(4):505-10. PMID:118304
[2] AbdelKhalek A, et al. Screening for potent and selective anticlostridial leads among FDA-approved drugs. J Antibiot (Tokyo). 2020 Mar 4. DOI:10.1038/s41429-020-0288-3 |
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| Company Name: |
SynAsst Chemical.
|
| Telephone: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
| Company Name: |
cjbscvictory
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|