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369377-66-2

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369377-66-2 Structure

369377-66-2 Structure
IdentificationBack Directory
[Name]

BigLEN (rat)
[CAS]

369377-66-2
[Synonyms]

BigLEN (rat)
[Molecular Formula]

C76H128N24O23
[MDL Number]

MFCD31544499
[MOL File]

369377-66-2.mol
[Molecular Weight]

1746.01
Chemical PropertiesBack Directory
[density ]

1.52±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

3.44±0.20(Predicted)
[color ]

White to off-white
[Sequence]

Leu-Glu-Asn-Ser-Ser-Pro-Gln-Ala-Pro-Ala-Arg-Arg-Leu-Leu-Pro-Pro
Hazard InformationBack Directory
[Uses]

BigLEN(rat) is a potent GPR171 agonist with an EC50 of 1.6 nM[1].
[References]

[1] Gomes I, et al. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013;110(40):16211-16216 DOI:10.1073/pnas.1312938110
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