| Identification | Back Directory | [Name]
ethyl 5-(acetyloxy)-2-({[amino(imino)methyl]sulfanyl}methyl)-6-bromo-1-phenyl-1H-indole-3-carboxylate | [CAS]
369606-71-3 | [Synonyms]
Antituberculosis agent-3
ethyl 5-(acetyloxy)-2-({[amino(imino)methyl]sulfanyl}methyl)-6-bromo-1-phenyl-1H-indole-3-carboxylate
1H-Indole-3-carboxylic acid, 5-(acetyloxy)-2-[[(aminoiminomethyl)thio]methyl]-6-bromo-1-phenyl-, ethyl ester | [Molecular Formula]
C21H20BrN3O4S | [MOL File]
369606-71-3.mol | [Molecular Weight]
490.37 |
| Hazard Information | Back Directory | [Uses]
Antituberculosis agent-3 (Compound 2) is an antituberculosis agent. Antituberculosis agent-3 shows anti-mycobacterial activity, and can inhibit M. tuberculosis H37Rv strain growth (MIC=12.5 μg/mL)[1]. | [References]
[1] Paptawan Thongdee, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22. DOI:10.1021/acs.jcim.2c00531 |
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