| Identification | Back Directory | [Name]
4(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)- | [CAS]
37109-98-1 | [Synonyms]
dH2U
2-Deoxy-2’-deoxyuridine
4-Pyrimidinone-2’-deoxyriboside
4(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)- | [Molecular Formula]
C9H12N2O4 | [MDL Number]
MFCD34548971 | [MOL File]
37109-98-1.mol | [Molecular Weight]
212.21 |
| Hazard Information | Back Directory | [Uses]
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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