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374675-19-1

374675-19-1 Structure

374675-19-1 Structure
IdentificationBack Directory
[Name]

Kisspeptin-14 human
[CAS]

374675-19-1
[Synonyms]

Kisspeptin-14 human
[Molecular Formula]

C82H112N22O21
[MOL File]

374675-19-1.mol
[Molecular Weight]

1741.9
Chemical PropertiesBack Directory
[density ]

1.49±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

3.72±0.10(predicted)
[color ]

White to off-white
[Sequence]

Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Hazard InformationBack Directory
[Uses]

Kisspeptin-14 human is a peptide hormone encoded by the KiSS-1 gene. Kisspeptin-14 human, along with several other similar peptide hormones, is produced from a common precursor protein by cleavage by different proteases. Kisspeptin-14 human has the same receptor binding efficiency and potency as full-length kisspeptin. Kisspeptin-14 human binds to its receptor GPR54 and is able to activate this G protein-coupled receptor and activate multiple intracellular signaling pathways. Kisspeptin-14 human can be used to study reproductive development and tumor metastasis[1].
[References]

[1] Tena-Sempere M. GPR54 and kisspeptin in reproduction[J]. Human Reproduction Update, 2006, 12(5): 631-639. DOI:10.1093/humupd/dml023
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