| Identification | Back Directory | [Name]
GTP-GAMMA-S SODIUM SALT | [CAS]
37589-80-3 | [Synonyms]
GTP-γ-S
GTP-GAMMA-S
GTP-GAMMA-S, NA
GTP-GAMMA-S SODIUM SALT
guanosine5’-o-(3-thiotriphosphate
Guanosine 5'-γ-thiotriphosphoric acid
Guanosine 5'-(γ-thiotriphosphoric acid)
Guanosine 5'-O-(γ-thiotriphosphoric acid)
5'-Guanylyloxyphosphonyloxythiophosphonic acid
GUANOSINE-5'-O-(3-THIOTRIPHOSPHATE) SODIUM SALT
GUANOSINE-5'-O-(3-THIOTRIPHOSPHORIC ACID), SODIUM
GUANOSINE-5'-(GAMMA-THIO)-TRIPHOSPHATE, SODIUM SALT
GUANOSINE-5'-[GAMMA-THIO]TRIPHOSPHATE TETRASODIUM SALT
guanosine-5’-o-(3-thiotriphosphate),(gtp-g-s),sodiumsalt
Guanosine-5′-[γ-thio]triphosphate tetrasodium salt solution
Guanosine-5μ-[γ-thio]triphosphate solution tetrasodium salt
Guanosine5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid | [Molecular Formula]
C10H12N5Na4O13P3S | [MDL Number]
MFCD03791271 | [MOL File]
37589-80-3.mol | [Molecular Weight]
627.17 |
| Chemical Properties | Back Directory | [density ]
2.68±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C (-15°C to -25°C) | [form ]
solution (deep frozen) | [pka]
0.67±0.50(Predicted) | [color ]
white | [Water Solubility ]
water: soluble |
| Hazard Information | Back Directory | [Uses]
GTP-γ-S has been used:
- in G-Protein activation assay to assess the functionality of protease-activated receptor 4 (PAR4)
- in fluorimetric guanine nucleotide exchange assay of G protein alpha subunits (Gα)
- to monitor the Rac family small guanosine triphosphatase (GTPase) 2 (Rac2)-stimulated activity of phospholipase Cγ2 mutants
| [Definition]
ChEBI: Guanosine 5'-[gamma-thio]triphosphate is a nucleoside triphosphate analogue. It is functionally related to a GTP. | [General Description]
Guanosine 5′-O-(3-thiotriphosphate), tetralithium salt (GTP-γ-S) is a non-hydrolysable analog of GTP. It is an inhibitor of phosphodiesterase in photoreceptors. | [Biochem/physiol Actions]
Guanosine 5′-O-(3-thiotriphosphate) (GTP-γ-S) activates guanine-nucleotide-binding proteins and is slowly hydrolyzed enzymatically. It inhibits guanosine triphosphatase (GTPases) more potently than guanosine triphosphate (GTP), |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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