ChemicalBook--->CAS DataBase List--->376616-73-8

376616-73-8

376616-73-8 Structure

376616-73-8 Structure
IdentificationBack Directory
[Name]

ZQ-16
[CAS]

376616-73-8
[Synonyms]

ZQ-16
2-HTP
ZQ-16 >=98% (HPLC)
2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone
4(3H)-Pyrimidinone, 2-(hexylthio)-6-hydroxy-
[Molecular Formula]

C10H16N2O2S
[MOL File]

376616-73-8.mol
[Molecular Weight]

228.31
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
[InChI]

1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14)
[InChIKey]

UYXOAKRMLQKLQX-UHFFFAOYSA-N
[SMILES]

CCCCCCSC1=NC(O)=CC(O)=N1
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Uses]

ZQ 16, is a potent and selective agonist for medium-chain free fatty acid receptor GPR84 (G protein-coupled receptor 84). It activates GPR84-mediated calcium mobilization, inhibits cAMP accumulation, phosphorylation of ERK1/2, receptor desensitization and internalization, and receptor-β-arrestin interaction.
[Biological Activity]

ZQ-16 is a potent and selective agonist for medium-chain free fatty acid receptor GPR84 (G protein-coupled receptor 84). ZQ-16 activates GPR84-mediated calcium mobilizationinhibition of cAMP accumulationphosphorylation of ERK1/2receptor desensitization and internalizationand receptor-β-arrestin interaction.
Spectrum DetailBack Directory
[Spectrum Detail]

ZQ-16(376616-73-8)1HNMR
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