| Identification | Back Directory | [Name]
tebufloquin | [CAS]
376645-78-2 | [Synonyms]
tebufloquin
Tebufloquin Standard
6-(tert-Butyl)-8-fluoro-2,3-dimethylquinolin-4-yl acetate | [Molecular Formula]
C17H20FNO2 | [MOL File]
376645-78-2.mol | [Molecular Weight]
289.345 |
| Hazard Information | Back Directory | [Uses]
Tebufloquin is a fungicide used in the preparation of new quinoline derivatives against Pyricularia oryae and Erysiphe cichoracearum. | [Definition]
ChEBI:Tebufloquin is a member of the class of quinolines that is quinoline which is substituted at positions 2 and 3 by methyl groups and at positions 4, 6, and 8 by acetoxy, tert-butyl, and fluorine, respectively. A fungicide developed mainly for the control of rice blast (Magnaporthe grisea), it has also been found to be effective against fungal diseases in soya beans and tomatoes. It has a role as an antifungal agrochemical. It is a member of quinolines, an organofluorine compound and an acetate ester. | [Production Methods]
The commercial production of tebufloquin involves the synthesis of a substituted quinoline core, specifically 6-tert-butyl-8-fluoro-2,3-dimethylquinolin-4-yl acetate. The process includes electrophilic substitution, fluorination, and acetylation steps, followed by purification to yield a high-purity crystalline powder. | [Mechanism of action]
Protective and curative. Inhibits mitochondrial electron transport processes and so disrupts energy production | [Pesticide Type]
Fungicide |
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