| Identification | Back Directory | [Name]
questin | [CAS]
3774-64-9 | [Synonyms]
questin
1,6-Dihydroxy-3-methyl-8-methoxy-9,10-anthraquinone
1,6-Dihydroxy-8-methoxy-3-methyl-9,10-anthracenedione
9,10-Anthracenedione, 1,6-dihydroxy-8-methoxy-3-methyl- | [Molecular Formula]
C16H12O5 | [MDL Number]
MFCD18452287 | [MOL File]
3774-64-9.mol | [Molecular Weight]
284.26 |
| Chemical Properties | Back Directory | [Melting point ]
301-303 °C | [Boiling point ]
557.0±50.0 °C(Predicted) | [density ]
1.448±0.06 g/cm3(Predicted) | [solubility ]
Dichloromethane: soluble
DMSO: soluble
Ethanol: soluble
Methanol: soluble | [form ]
Solid | [pka]
6.50±0.20(Predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
Questin is an antibacterial agent isolated from marine Aspergillus flavipes. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 μg/mL, 62.5 μg/mL, 62.5 μg/mL, and 125 μg/mL[1]. | [Definition]
ChEBI: Questin is a dihydroxyanthraquinone that is 1,6-dihyroxy-9,10-anthraquinone which is substituted by a methyl group at position 3 and a methoxy group at position 8. It is functionally related to an emodin. It is a conjugate acid of a questin-2-olate. | [References]
[1] Lei Guo, et al. Optimized production and isolation of antibacterial agent from marine Aspergillus flavipes against Vibrio harveyi. 3 Biotech. 2017 Dec;7(6):383. DOI:10.1007/s13205-017-1015-z |
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