| Identification | Back Directory | [Name]
1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]- | [CAS]
37743-74-1 | [Synonyms]
2-Amino-1-(4-methylbenzyl)benzimidazole
1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]- | [Molecular Formula]
C15H15N3 | [MOL File]
37743-74-1.mol | [Molecular Weight]
237.3 |
| Chemical Properties | Back Directory | [Boiling point ]
462.0±48.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [storage temp. ]
Room Temperature | [solubility ]
CHCl3, DCM, MeOH, Acetone, Acetonitrile | [pka]
6.66±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
2-Amino-1-(4-methylbenzyl)benzimidazole is an intermediate in the synthesis of Yan 7874 (Y100510) which is a potential drug in the treatment of narcolepsy, insomnia and maybe other sleep and vigilance disorders. Yan 7874 is a orexin 2 receptor agonist, yet the efficacy of Yan 7874 also appears weak, and should also be clearly improved to make it useful as a drug or research tool. |
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