ChemicalBook--->CAS DataBase List--->378763-92-9

378763-92-9

378763-92-9 Structure

378763-92-9 Structure
IdentificationBack Directory
[Name]

HUMAN IL-8
[CAS]

378763-92-9
[Synonyms]

IL-8
RHIL-8
HUMAN IL-8
HUMAN CXCL8
IL-8, HUMAN
IL-8 (77AA), HUMAN
IL-8 (72AA), HUMAN
HUMAN INTERLEUKIN 8
IL-8 [HOMO SAPIENS]
INTERLEUKIN 8 HUMAN
REC MONOCYTE IL-8 (HUMAN)
IL-8/72 AMINO ACIDS HUMAN
INTERLEUKIN-8 (72AA), HUMAN
INTERLEUKIN-8 (77AA), HUMAN
REC ENDOTHELIAL IL-8 (HUMAN)
Mouse Anti Human Interleukin-8
INTERLEUKIN-8, HUMAN, RECOMBINANT
REC MONOCYTE INTERLEUKIN-8 (HUMAN)
REC ENDOTHELIAL INTERLEUKIN-8 (HUMAN)
INTERLEUKIN-8(MONOCYTE-DERIVED), HUMAN
INTERLEUKIN-8, HUMAN, RECOMBINANT, E COLI
INTERLEUKIN-8(ENDOTHELIAL CELL-DERIVED), HUMAN
2-Furancarboxylic acid, 5-[1-amino-8,9-dihydro-8,8-dimethyl-5-(4-morpholinyl)-6H-pyrano[4,3-d]thieno[2,3-b]pyridin-2-yl]-
[Molecular Formula]

C21H23N3O5S
[MDL Number]

MFCD00131404
[MOL File]

378763-92-9.mol
[Molecular Weight]

429.49
Chemical PropertiesBack Directory
[Boiling point ]

715.1±60.0 °C(Predicted)
[density ]

1.391±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

lyophilized powder
[pka]

2.60±0.10(Predicted)
[biological source]

human
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[HS Code ]

3504009000
Hazard InformationBack Directory
[Uses]

Interleukin-8 (IL-8) human has ben used to:
  • measure neutrophil chemotoxis
  • study the uptake of apoptotic cells by meningothelial cells
  • study the effect of IL-8 on expression and secretion of urocortin-1 by human umbilical vein endothelial cells
[Biochem/physiol Actions]

Interleukin-8 (IL-8) was formerly called monocyte-derived neutrophil chemotactic factor. It belongs to the chemokine α or C-X-C family. Like other members of this family, the mature form of IL-8 has four cysteine residues and the first two cysteine residues are separated by glutamine. IL-8 shows chemotactic activity in vitro for T cells, neutrophils and basophils. Mutation in IL-8 can increase risk to acute pancreatitis.
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