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38183-47-0

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38183-47-0 Structure

38183-47-0 Structure
IdentificationBack Directory
[Name]

6H-Purin-6-one, 1,9-dihydro-9-α-D-ribofuranosyl-
[CAS]

38183-47-0
[Synonyms]

Alpha-inosine
Difelikefalin Impurity 2
Inosine Impurity 5(alpha-Inosine)
(2S,3R,4S,5R)-2-(6-Hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
[Molecular Formula]

C10H12N4O5
[MOL File]

38183-47-0.mol
[Molecular Weight]

268.23
Chemical PropertiesBack Directory
[Melting point ]

218-220 °C
[Boiling point ]

797.9±60.0 °C(Predicted)
[density ]

1.576 g/cm3
[pka]

8.92±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Alpha-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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