| Identification | Back Directory | [Name]
5-METHOXY-2-NITROBENZONITRILE | [CAS]
38469-84-0 | [Synonyms]
3-Cyano-4-nitroanisole
5-METHOXY-2-NITROBENZONITRILE
Benzonitrile, 5-methoxy-2-nitro-
3-Cyano-4-nitroanisole, 2-Cyano-4-methoxynitrobenzene | [Molecular Formula]
C8H6N2O3 | [MDL Number]
MFCD09056823 | [MOL File]
38469-84-0.mol | [Molecular Weight]
178.14 |
| Chemical Properties | Back Directory | [Melting point ]
96 °C | [Boiling point ]
352.2±32.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [Appearance]
Light brown to yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
Step 2: Synthesis of 5-methoxy-2-nitrobenzonitrile
To a 100 mL round bottom flask was added 5-methoxy-2-nitrobenzamide (2.1 g, 0.01 mol), trifluoroacetic anhydride (2.2 mL), triethylamine (2.9 mL) and dichloromethane (30 mL). The reaction mixture was stirred at room temperature for 1 hour. After completion of the reaction, the reaction mixture was washed with distilled water (30 mL × 2). The organic layer was separated and dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure to give 1.75 g (92% yield) of white solid product. Mass spectrometry (MS) showed m/z: 179 ([M + H]+). | [References]
[1] Patent: US2010/120741, 2010, A1. Location in patent: Page/Page column 59 |
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