| Identification | Back Directory | [Name]
(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261) | [CAS]
385800-16-8 | [Synonyms]
MX 1094
LT-NS 001
Naproxen etemesil
(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate
(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261)
2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, 2-(methylsulfonyl)ethyl ester, (αS)- | [Molecular Formula]
C17H20O5S | [MDL Number]
MFCD30532651 | [MOL File]
385800-16-8.mol | [Molecular Weight]
336.4 |
| Chemical Properties | Back Directory | [Boiling point ]
542.0±35.0 °C(Predicted) | [density ]
1.238±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Naproxen Etemesil, is a lipophilic, non-acidic, inactive prodrug of naproxen, that is a well known nonsteroidal anti-inflammatory drug. | [in vivo]
Naproxen exerts an anti-inflammatory and antifibrotic effect in mouse model of bleomycin-induced lung fibrosis. Naproxen also downregulates TGF-β levels and Smad3/4 complex formation[2]. Naproxen is shown to inhibit the time-courses of pain, fever and PGE2 with similar potencies (IC50=27, 40, 13 μM)[3]. |
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