| Identification | Back Directory | [Name]
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate | [CAS]
3859-65-2 | [Synonyms]
BNKY017-TA02
Triamcinolone 21-Acetate
Triamcinolone EP Impurity B
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate
(11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione
(11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,16,17-trihydroxy-, (11β,16α)-
2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate | [Molecular Formula]
C23H29FO7 | [MOL File]
3859-65-2.mol | [Molecular Weight]
436.47 |
| Chemical Properties | Back Directory | [Melting point ]
212-215 °C(Solv: acetone (67-64-1); ethyl ether (60-29-7)) | [Boiling point ]
596.0±50.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [solubility ]
DMSO (Slightly), Methanol (Slightly, Sonicated, Heated) | [form ]
Solid | [pka]
11.52±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
Triamcinolone 21-acetate is a synthetic anti-inflammatory drug with a triamcinolone core. It has been used for the treatment of inflammatory conditions such as arthritis and allergic disorders. The mechanism of action is unknown, but it is thought to involve the inhibition of prostaglandin synthesis by inhibiting enzymes that are involved in prostaglandin biosynthesis. Triamcinolone 21-acetate is effective against rheumatoid arthritis and other inflammatory disorders. This drug also has anti-bacterial activity, which may be due to its ability to inhibit cell membrane function or interfere with protein synthesis.
| [Uses]
Triamcinolone 21-Acetate is an impurity of Triamcinolone (T767160), a glucocorticoid used as an antiasthmatic. |
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