| Identification | Back Directory | [Name]
Triptonide | [CAS]
38647-11-9 | [Synonyms]
PG 492
TRIPTONIDE
NSC 165677
Triptonide USP/EP/BP
14-Deoxy-14-oxotriptolide
Triptolide,14-deoxy-14-oxo
TRIPTONIDE(PRIMARY STANDARD)
Triptonide, 98%, from Peucedanum praeruptorum Dunn
(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-6a-Isopropyl-8b-methyl-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione
Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione, 3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)- | [Molecular Formula]
C20H22O6 | [MDL Number]
MFCD00210566 | [MOL File]
38647-11-9.mol | [Molecular Weight]
358.39 |
| Chemical Properties | Back Directory | [Melting point ]
251～252℃ | [Boiling point ]
581.1±50.0 °C(Predicted) | [density ]
1.48±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
Dichloromethane (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White to Pale Beige |
| Hazard Information | Back Directory | [Uses]
Triptonide is a Triptolide (T815600) analogue used in the preparation of cytotoxic fluorinated Triptolide. | [Definition]
ChEBI:Triptonide is a diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii. It has a role as an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent. It is a cyclic ketone, an organic heteroheptacyclic compound, a diterpene triepoxide and a butenolide. | [target]
ERK | IL Receptor | GSK-3 | p38MAPK | Wnt/β-catenin | [storage]
Store at -20°C |
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