| Identification | Back Directory | [Name]
8-AMINOADENOSINE | [CAS]
3868-33-5 | [Synonyms]
NSC 90394
8-NH2-Ado
8-Amionadenosine
8-AMINOADENOSINE
Adenosine, 8-amino-
8-Amino-D-adenosine
8-AMINOADENOSINE USP/EP/BP
6,8-DiaMino-9-β-D-ribofuranosyl- 9H-purine
6,8-Diamino-9-beta-D-ribofuranosyl-9H-purine
9H-Purine, 6,8-diamino-9-.beta.-D-ribofuranosyl-
2-(6,8-diamino-9-purinyl)-5-(hydroxymethyl)oxolane-3,4-diol
(2R,3R,4S,5R)-2-(6,8-Diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | [Molecular Formula]
C10H14N6O4 | [MDL Number]
MFCD00047230 | [MOL File]
3868-33-5.mol | [Molecular Weight]
282.26 |
| Chemical Properties | Back Directory | [Melting point ]
180-185°C dec. | [Boiling point ]
747.1±70.0 °C(Predicted) | [density ]
2.25 | [storage temp. ]
-20°C Freezer | [solubility ]
H2O: soluble2mg/mL, clear (warmed) | [form ]
powder | [pka]
13.07±0.70(Predicted) | [color ]
white to beige | [Water Solubility ]
H2O: 2mg/mL, clear (warmed) | [InChI]
1S/C10H14N6O4/c11-7-4-8(14-2-13-7)16(10(12)15-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,15)(H2,11,13,14) | [InChIKey]
DVGWFQILDUEEGX-UHFFFAOYSA-N | [SMILES]
[n]2(c3ncnc(c3nc2N)N)C1OC(C(C1O)O)CO |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
25 | [Safety Statements ]
45 | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
3 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
The purine nucleoside analog | [Biological Activity]
8-Aminoadenosinea ribose nucleosidereduces cellular ATP levels and inhibits mRNA synthesis. 8-Aminoadenosine also inhibits transcription and polyadenylation. 8-Aminoadenosine potently inhibits varies breast cancer cell lines proliferation and activates cell death independent of p53. 8-NH2-Ado is highly cytotoxic to other cancer cell lines. | [IC 50]
mTOR |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
| Company Name: |
NewCan Biotech Limited
|
| Telephone: |
+86-571-86912261 19975279805 |
| Website: |
https://www.newcanbio.com/ |
| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Telephone: |
+86-029-81138252 +86-173 9270 1263 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-222/ |
|