| Identification | Back Directory | [Name]
PRASUGREL HYDROCHLORIDE | [CAS]
389574-19-0 | [Synonyms]
Ridomil 72WP
Prasugrel HCI
Prasugrel HCl
Unii-G89jq59I13
Effient Hydrochloride
Prasugrel hydrochloric
Prasugrenhydrochloride
PRASUGREL HYDROCHLORIDE
LY 640315 Hydrochloride
PCR 4099 (hydrochloride)
Prasugrel
(Discontinued)
Prasugrel hydrochloride, >=99%
Prasugrel Hydrochloride (PCR 4099
TIANFU-CHEM--PRASUGREL HYDROCHLORIDE
5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-2H,4H,5H,6H,7H,7aH-thieno[3,2-c]pyridin-2-one
acetic acid [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] ester
[5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate,hydrochloride
5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone hydrochloride
Ethanone,2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-,hydrochloride (1:1)
Prasugrel Hydrochloride
5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-
tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
Prasugrel HydrochlorideQ: What is
Prasugrel Hydrochloride Q: What is the CAS Number of
Prasugrel Hydrochloride Q: What are the applications of
Prasugrel Hydrochloride | [EINECS(EC#)]
627-126-4 | [Molecular Formula]
C20H20FNO3S.ClH | [MDL Number]
MFCD11867705 | [MOL File]
389574-19-0.mol | [Molecular Weight]
409.907 |
| Chemical Properties | Back Directory | [Melting point ]
>173?C (dec.) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) | [form ]
Solid | [color ]
White to Pale Brown | [Major Application]
pharmaceutical | [InChI]
InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H | [InChIKey]
JALHGCPDPSNJNY-UHFFFAOYSA-N | [SMILES]
N1(CCC2SC(OC(C)=O)=CC=2C1)C(C1C=CC=CC=1F)C(=O)C1CC1.Cl |
| Hazard Information | Back Directory | [Description]
Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation. | [Chemical Properties]
White to Off-White Solid | [Uses]
A novel antiplatelet agent; it is a third-generation thienopyridine.
y induce increased incidence of bleeding in patient with acute coronary syndrome | [in vivo]
In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM.
Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h. | [IC 50]
P2Y12 Receptor |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Aemon Chemical
|
| Telephone: |
0086-755-86198205 |
| Website: |
www.aemonchem.com |
|