| Identification | Back Directory | [Name]
2-((3-(dimethylamino)propyl)amino)-1,4-dihydroxyanthra-9,10-quinone | [CAS]
3900-43-4 | [Synonyms]
MYRAA
MYRA-A
MYRA A
NSC339585
NSC-339585
NSC 339585
2-((3-(dimethylamino)propyl)amino)-1,4-dihydroxyanthra-9,10-quinone | [Molecular Formula]
C19H20N2O4 | [MOL File]
3900-43-4.mol | [Molecular Weight]
340.373 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: >10mg/mL | [form ]
powder | [color ]
red | [InChI]
1S/C19H20N2O4.ClH/c1-21(2)9-5-8-20-13-10-14(22)15-16(19(13)25)18(24)12-7-4-3-6-11(12)17(15)23;/h3-4,6-7,10,20,22,25H,5,8-9H2,1-2H3;1H | [InChIKey]
ZVKHFHKBUHMRPU-UHFFFAOYSA-N | [SMILES]
Cl.CN(C)CCCNc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1O |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1 |
| Hazard Information | Back Directory | [Description]
MYRA-A is an inducer of apoptosis in a Myc-dependent manner. It acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction. | [Uses]
MYRA-A is a potent apoptosis inducer in a Myc-dependent manner. MYRA-A inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins. MYRA-A inhibits cell viability[1]. | [References]
[1] Mo H, et al. Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6344-9. DOI:10.1073/pnas.0601418103 |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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