| Identification | Back Directory | [Name]
CUPRESSUFLAVONE TRIHYDRATE | [CAS]
3952-18-9 | [Synonyms]
CUPRESSUFLAVONE
8,8''-Biapigeninyl
CUPRESSUFLAVONE WITH HPLC
CUPRESSUFLAVONE TRIHYDRATE
CUPRESSUFLAVONE Trihydrate hplc
CUPRESSUFLAVONE TRIHYDRATE WITH HPLC
4',4''',5,5'',7,7''-HEXAHYDROXY-8,8''-BIFLAVONE
5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)[8,8'-bi(4H-1-benzopyran)]-4,4'-dione | [Molecular Formula]
C30H18O10 | [MDL Number]
MFCD00270166 | [MOL File]
3952-18-9.mol | [Molecular Weight]
538.46 |
| Chemical Properties | Back Directory | [Melting point ]
>400°C | [Boiling point ]
927.0±65.0 °C(Predicted) | [density ]
1.656±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
5.43±0.40(Predicted) | [color ]
Light yellow to yellow | [LogP]
3.070 (est) |
| Hazard Information | Back Directory | [Uses]
Cupressuflavone is a natural product that can be found in Cupressus macrocarpa. Cupressuflavone exhibits anti-inflammatory and antiulcerogenic activities. Cupressuflavone also show protective effects against CCl4-induced hepato- and nephrotoxicity in mice[1][2][3]. | [Definition]
ChEBI: A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-8 of the two chromene rings respectively. Isolated from Cupressus sempervirens and Juniperus occidentalis, i
exhibits free radical scavenging and antielastase activities. | [References]
[1] Al-Sayed E, et, al. Protective role of Cupressuflavone from Cupressus macrocarpa against carbon tetrachloride-induced hepato- and nephrotoxicity in mice. Planta Med. 2014 Dec;80(18):1665-71. DOI:10.1055/s-0034-1383211
[2] Al-Sayed E, et, al. Anti-inflammatory and analgesic activities of cupressuflavone from Cupressus macrocarpa: Impact on pro-inflammatory mediators. Drug Dev Res. 2018 Feb;79(1):22-28. DOI:10.1002/ddr.21417
[3] Koriem KMM, et, al. Protective effect of Cupressus sempervirens extract against indomethacin-induced gastric ulcer in rats. Interdiscip Toxicol. 2015 Mar;8(1):25-34. DOI:10.1515/intox-2015-0006 |
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